Stress Immune System And Age

Stress Immune System And Age



Stress,​ immune system and​ age
As ageing is​ associated with immunological changes,​ the​ effects of​ stress and​ age are interlinked where a​ deregulation of​ the​ immune function can have a​ significant impact on​ physical health. ​
On the​ other hand stess can both enhance and​ increase the​ effects of​ aging,​ with older adults often showing greater immunological impairment to​ stress than younger adults. ​
Therefore a​ good immune response is​ essential to​ our good health. ​
In the​ same way immunological alterations and​ disturbances can influence the​ progression and​ severity of​ a​ variety of​ disorders and​ diseases,​ including stress related disorders. ​

Also stressful experiences very early in​ life can alter the​ responsiveness of​ the​ nervous system and​ immune system. ​
it​ is​ possible that prenatal or​ early life stress may increase the​ likelihood of​ altered immune responses to​ stress in​ late life. ​
One such alteration to​ the​ immune system includes a​ decrease in​ the​ ability of​ white blood cells immune cells to​ carry out their key functions. ​
One great example is​ temporary stress as​ seen in​ students during examination stress. ​
This has been seen to​ slow down wound healing. ​
Children of​ mothers who are routinely stressed during their pregnancy show decrease in​ immune function compared to​ children of​ undisturbed pregnancies. ​
Similarly young children who experience abuse or​ neglect show abnormal cortisol levels indicative of​ a​ dysregulated stress response. ​
Cortisol is​ a​ hormone secreted by the​ adrenal glands and​ involved in​ glucose metabolism,​ blood pressure regulation,​ maintenance of​ insulin release,​ suppression of​ inflammatory responses. ​
Cortisol is​ elevated following several stress disorders. ​
Several stressful experiences can cause in​ areas of​ the​ brain involved in​ memory an imprinting during fetal development and​ early life can alter the​ responsiveness of​ the​ endocrine,​ immune,​ and​ central nervous systems for many years. ​
An understanding of​ such interlinked effects of​ stress and​ age is​ important to​ understand and​ to​ determine the​ mechanisms involved,​ so that we can develop effective interventions in​ early and​ late life.




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