Scientists Discover Links Between Hair Loss And Genetics

Scientists Discover Links Between Hair Loss And Genetics



Scientists discover links between hair loss and ​ genetics
Scientists from the​ University of​ Bonn recently discovered a​ gene that is​ responsible for​ a​ hereditary form of​ hair loss known as​ Hypotrichosis simplex. ​
The research is​ the​ firstever to​ identify a​ specific receptor that is​ essential for​ hair growth. ​
The researchers said that their findings will lead to​ new breakthroughs that could resolve the​ problem of​ hair loss. ​

Although Hypotrichosis simplex is​ very uncommon,​ it​ may prove critical in​ understanding the​ mechanisms of​ hair growth,​ says project leader Dr. ​
Regina Betz from Bonns Institute of​ Human Genetics. ​
Individuals affected by this condition usually go bald during childhood. ​
Alopecia or​ the​ process of​ hair loss especially around the​ scalp progresses as​ an individual gets older. ​

As examined in​ the​ project,​ the​ researchers found out that the​ cause of​ Hypotrichosis simplex is​ genetic abnormality that restricts certain receptor structures on​ the​ surface of​ hair follicle cells from forming properly. ​
These receptors play an essential role in​ hair growth that was previously unknown to​ scientists. ​

Dr. ​
Markus N?then,​ chairman of​ Genetic Medicine at ​ Bonn Universitys Life & Brain Centre said that the​ defective receptor structure falls into the​ category of​ what are known as​ Gproteincoupled receptors. ​
This is​ good news,​ because,​ they are particularly well suited as​ points of​ impact for​ ​Drug​ treatments,​ he said. ​
The researchers were also able to​ pinpoint an endogenous messenger that attaches in​ the​ hair follicle to​ the​ receptor.
Researchers believe that the​ study opens up opportunities for​ future studies about hair loss. ​
We can now search selectively for​ related substances that may be used in​ therapies for​ hair loss,​ say Dr. ​
Ivar von Kügelgen of​ Bonn’s Institute of​ Pharmacology and ​ Toxicology. ​
Because of​ the​ study,​ the​ possibility of​ developing medicines that will benefit patients suffering from hair loss has significantly improved.




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