Vitamin D And 8230 Kidney Disease The Hidden Connection With Serious
Consequences

Vitamin D And 8230 Kidney Disease The Hidden Connection With Serious Consequences



Vitamin D And…Kidney Disease? the​ Hidden Connection With Serious Consequences
You may know that the​ sun and certain foods are good sources of​ vitamin D. But did you know that due to​ chronic kidney disease,​ millions of​ Americans cant convert the​ form of​ vitamin D produced by the​ sun or​ found in​ food and overthecounter vitamins into the​ active form of​ vitamin D used by the​ body? This means that even if​ youre taking vitamin D pills,​ getting adequate sunlight or​ eating foods rich in​ vitamin D,​ your bones and organs may be at​ risk due to​ a​ deficiency in​ active vitamin D.
Chronic Kidney Disease
Chronic kidney disease CKD is​ a​ condition in​ which kidney function slows and the​ kidneys stop doing critical jobs such as​ filtering toxins from the​ bloodstream.
The severity of​ CKD is​ classified in​ stages,​ with stage 5,​ also known as​ kidney failure or​ endstage renal disease ESRD,​ being the​ most severe. Patients with ESRD require dialysis,​ a​ procedure where several times a​ week for several hours their bloodstream is​ routed through a​ machine that filters toxins.
40 million Americans with
or at​ risk for chronic
kidney disease
Earlystage CKDbefore dialysis is​ necessaryis often undetected and can worsen with declines in​ kidney function.
According to​ the​ National Kidney Foundation,​ 20 million Americans1 in​ 9have CKD and another 20 million are at​ increased risk.
So what does CKD have to​ do with vitamin D,​ let alone
your bones?
Before the​ body can use vitamin D,​ it​ has to​ be activated. Inactive vitamin Dthe vitamin D you get in​ the​ form of​ overthecounter pills,​ food or​ sunlightis activated by two steps,​ one in​ the​ liver and the​ other in​ the​ kidneys.
Then,​ much like a​ key fits into a​ car ignition and starts the​ engine,​ activated vitamin D fits into vitamin D receptors located in​ numerous tissues and systems throughout the​ body and triggers processes that help maintain bone,​ the​ heart,​ the​ immune system and so on.
For people with CKD,​ however,​ their kidneys ability to​ activate adequate amounts of​ vitamin D deteriorates as​ their overall kidney function decreases. in​ fact,​ people with kidney disease may eventually lose the​ ability to​ activate vitamin D altogether.
Secondary
hyperparathyroidism
When levels of​ active vitamin D are low or​ inadequate within the​ body,​ a​ serious complication of​ CKD called secondary hyperparathyroidism SHPT can occur. SHPT can lead to​ a​ wide range of​ problems,​ including damage to​ bones and many vital organs.
How is​ SHPT prevented
and treated?
When CKD and SHPT are detected early,​ the​ conditions may be managed and disease progression may be slowed.
Remember,​ people with stage 3 or​ 4 CKD who develop SHPT cannot convert vitamin D into its active form within their own kidneys. Experts suggest that these patients with stage 3 or​ 4 CKD and SHPT take an activated form of​ vitamin D medicationwhich is​ available only by prescriptionto correct their vitamin D deficiency and thereby treat SHPT. Managing SHPT lowers risk for bone loss or​ fracture,​ cardiac complications and dangerous mineral and hormonal imbalances.




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